Studies have shown that acute hepatitis a check in the common false positive results

Researchers on May 13, the morbidity and mortality weekly report (MMWR 2005; 54:45 3-2005), no clinical symptoms or hepatitis a virus (HAV) infection patients with a history of exposure may get false positive results in a regular examination.

"In order to improve the anti HAV IgM positive predictive value examination, the doctor should be limited acute HAV infection of hepatitis a clinical laboratory examination in can see or HAV exposure suspicious patients", the first author, the United States Connecticut department of public health Ding Beike (z. f. Dembek) and colleagues said.

Their team studied Connecticut and Alaska anti HAV check IgM cases, research data and check the outpost 2003 county. In Connecticut, between 2002 and 2003, 127 people reported positive results, but only 108 people with acute HAV infection disease. In the remaining 19 is considered false positie, nine people do not have symptoms, 10 people have do not agree with the HAV clinical manifestations. In Alaska, between 2002 and 2004 report to the ministry of public health in Alaska had 27 cases were consistent with the HAV and 10 period positive cases. In the 10 cases, 7 people increased serum alanine transaminase (ALT), the other three people without symptoms. Outpost in 6 counties county in the study, CDC researchers found 140 anti HAV check IgM, only 53 of them (38%) are consistent with this definition, 25 do not conform to the definer HAV only 1 (4%) found in RNA, and conform to the definer of 34 (66%).

Most of the false positive all three data from no typical infection risk factors of the elderly. In fact, most people have negative checked again.

"Should stop using the HAV IgM resistance as a screening tool or part of the screening content used to examine the acute liver dysfunction patients", comment author writes, the doctor to have contact with the HAV IgM can make the immune prevention decision after exposure, but without clinical manifestations and patients with a history of exposure should be looking for other information.